By Alaric Dearment
Cambridge, Massachusetts-based Imara said Monday that it had raised the $63 million Series B funding round, led by new investors OrbiMed and Arix Bioscience. Other participants in the round included RA Capital, Rock Springs Capital and existing investors New Enterprise Associates, Pfizer Venture Investments, Lundbeckfonden Ventures, Bay City Capital and Alexandria Venture Investments.
Cambridge, Massachusetts-based Imara said Monday that it had raised the $63 million Series B funding round, led by new investors OrbiMed and Arix Bioscience. Other participants in the round included RA Capital, Rock Springs Capital and existing investors New Enterprise Associates, Pfizer Venture Investments, Lundbeckfonden Ventures, Bay City Capital and Alexandria Venture Investments.
Imara said it planned to use the money to fund development of its lead product candidate, IMR-687, which is currently in a Phase IIa trial in sickle cell disease, and move it into later-stage clinical trials. It also plans to fund the drug’s development as a potential treatment for beta-thalassemia, another blood disorder, and expand its pipeline.
“This is a transformative financing for Imara – one that will allow us to greatly expand our sickle cell disease clinical development, widen our reach into thalassemia and build an exciting pipeline,” CEO Rahul Ballal said in a statement. “We are pleased to be working with leading investors who share our vision for creating a company that helps change the lives of patients living with SCD and other hemoglobinopathies.”
IMR-687 is an inhibitor of phosphodiesterase-9, working on the same pathway as hydroxyurea, a generic chemotherapy drug commonly used to treat blood disorders and blood cancers. The difference, according to the company, is that it doesn’t have the safety issues that come with hydroxyurea. Hydroxyurea’s label carries a boxed warning for severely reduced blood counts and carcinogenicity.
The company announced preclinical and Phase I data in September 2017 showing that IMR-687’s mechanism of action could be effective against the red and white blood cell pathologies associated with SCD and that it could be safely dosed in humans at levels shown as effective in preclinical models.
IMR-687 is an inhibitor of phosphodiesterase-9, working on the same pathway as hydroxyurea, a generic chemotherapy drug commonly used to treat blood disorders and blood cancers. The difference, according to the company, is that it doesn’t have the safety issues that come with hydroxyurea. Hydroxyurea’s label carries a boxed warning for severely reduced blood counts and carcinogenicity.
IMR-687 is an inhibitor of phosphodiesterase-9, working on the same pathway as hydroxyurea, a generic chemotherapy drug commonly used to treat blood disorders and blood cancers. The difference, according to the company, is that it doesn’t have the safety issues that come with hydroxyurea. Hydroxyurea’s label carries a boxed warning for severely reduced blood counts and carcinogenicity.
The company announced preclinical and Phase I data in September 2017 showing that IMR-687’s mechanism of action could be effective against the red and white blood cell pathologies associated with SCD and that it could be safely dosed in humans at levels shown as effective in preclinical models.
Source. Medcitynews, Alaric Dearment, March 18, 2019
About Woewoda Communications
Woewoda Communications is one of Canada’s leading strategic communications and public relations firms. Located in Langley BC, the agency has built its reputation on creating and implementing integrated solutions that delivers what its clients value most: meaningful, positive, measurable, and impactful PR campaigns.
Our mission is to provide clients with inspired, integrated communications service. Our teams of PR professionals work with the Investment Community and Start-ups to design, implement, and manage communication strategies that help our clients bridge the information gap between them and their stakeholders.
Our PR services include Campaign building, Media PR, Community PR, Relationship PR, Venture Capital PR, Start-up PR, Private Equity PR, and Investor Relation Services (IR).
Whether its campaign building, media interaction, promoting a Venture Capital (VC) or a Private Equity (PE) and their investment portfolio, positioning a Start-up company, improving a company’s relationship with their community, organizing a major business event, or reaching out to investors, we have the PR team that can help our clients reach their goals.
Our Services. Strategic Communications, Public Relations and Investor Relations
Clients. Venture Capitalists, Private Equity Investors, Family Offices, Endowments/Trusts, Angel Investors, and Start-ups
Sectors. Information communication technology, life sciences, healthcare, artificial intelligence, robotics, clean energy, financial technology, internet of things, blockchain technology, and agribusiness
"We work with General Partners, Limited Partners, Corporate Investors and Presidents of Start-ups in Canada and the United States".
Source. Medcitynews, Alaric Dearment, March 18, 2019
About Woewoda Communications
Woewoda Communications is one of Canada’s leading strategic communications and public relations firms. Located in Langley BC, the agency has built its reputation on creating and implementing integrated solutions that delivers what its clients value most: meaningful, positive, measurable, and impactful PR campaigns.
Our mission is to provide clients with inspired, integrated communications service. Our teams of PR professionals work with the Investment Community and Start-ups to design, implement, and manage communication strategies that help our clients bridge the information gap between them and their stakeholders.
Our PR services include Campaign building, Media PR, Community PR, Relationship PR, Venture Capital PR, Start-up PR, Private Equity PR, and Investor Relation Services (IR).
Whether its campaign building, media interaction, promoting a Venture Capital (VC) or a Private Equity (PE) and their investment portfolio, positioning a Start-up company, improving a company’s relationship with their community, organizing a major business event, or reaching out to investors, we have the PR team that can help our clients reach their goals.
Our Services. Strategic Communications, Public Relations and Investor Relations
Clients. Venture Capitalists, Private Equity Investors, Family Offices, Endowments/Trusts, Angel Investors, and Start-ups
Sectors. Information communication technology, life sciences, healthcare, artificial intelligence, robotics, clean energy, financial technology, internet of things, blockchain technology, and agribusiness
"We work with General Partners, Limited Partners, Corporate Investors and Presidents of Start-ups in Canada and the United States".
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